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Antipsychotic Agents may enhance the serotonergic effect of Serotonin Modulators. Inhibition of mitochondrial complex I with rotenone or gas-1 RNAi in C. elegans elevates CeACAD10 mRNA and CeACAD10 reporter expression ( Figures 2 Figures 2A and 2B ). In young patients (younger than 40 years) with signs of parkinsonism and tremor, a serum copper, serum ceruloplasmin, 24-hour urinary copper, and slit-lamp examination are necessary to rule out Wilson's disease.
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